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Symbol
Name
ID

Sh3bp2
SH3-domain binding protein 2
MGI:1346349

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

increased B cell apoptosis

abnormal osteoclast differentiation

decreased B cell proliferation

impaired macrophage phagocytosis

decreased transitional stage B cell number

decreased pro-B cell number

abnormal B cell number

decreased B-1 B cell number

increased marginal zone B cell number

increased pre-B cell number

increased osteoclast cell number

increased monocyte cell number

increased spleen red pulp amount

abnormal spleen marginal zone morphology

abnormal B cell physiology

decreased IgA level

decreased IgG1 level

decreased IgG3 level

decreased IgM level

decreased immunoglobulin level

abnormal marginal zone B cell physiology

abnormal macrophage physiology

abnormal osteoclast physiology

Availability

Mouse Genotype

Sh3bp2^tm1.1Ics/Sh3bp2^tm1.1Ics

Sh3bp2^tm1Bjro/Sh3bp2^tm1Bjro

Sh3bp2^tm1Geha/Sh3bp2^tm1Geha

Sh3bp2^tm1Rtpl/Sh3bp2^tm1Rtpl

Sh3bp2^tm1.1Ics/Sh3bp2⁺

Sh3bp2^tm1Bjro/Sh3bp2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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